Data presented at the 2020 annual congress of the European Society of Medical Oncology (ESMO) show long-term progression-free survival (PFS) benefit versus placebo for Lynparza (olaparib).
AstraZeneca (LSE: AZN) and Merck & Co (NYSE: MRK) are testing the PARP blocker as a first-line maintenance treatment in people with newly diagnosed, advanced BRCA-mutated ovarian cancer.
People in the trial, dubbed SOLO-1, had had a complete or partial response following platinum-based chemotherapy. Five-year follow-up showed a reduction in the risk of disease progression or death by 67%.
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