Ensysce and Quotient partnership on opioid pain drug

1 September 2022

USA-based clinical-stage biotech Ensysce Biosciences and the UK’s Quotient Sciences, a drug development and manufacturing accelerator, have entered a partnership to support the development and clinical testing of PF614-MPAR.

PF614-MPAR is a novel opioid combination product for the potential treatment of chronic pain that is designed to prevent both abuse and overdose.

Quotient Sciences is currently using its integrated Translational Pharmaceutics platform to identify a PF614-MPAR formulation that allows conversion into oxycodone within the prescribed dose range but reduces conversion to oxycodone at higher than prescribed dose levels in an overdose scenario.

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