Italian biopharma company Dompé has conducted the first study looking at the combination of its reparixin with standard chemotherapy and announced promising results from preliminary data at the San Antonio Breast Cancer Symposium.
Research carried out at several centers in the USA confirms the safety and tolerability of the combination of standard chemo with Dompé’s reparixin, an oral inhibitor of CXCR 1/2, which has a unique mechanism enabling it to act directly on cancer stem cells and slow down replication. This is effective in HER-2 negative metastatic breast cancer, and 12%-17% of cases of breast cancer are triple negative.
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