Daiichi Sankyo signs up on two oncology deals
Japanese pharma major Daiichi Sankyo (TYO: 4568) had a busy day, signing up on two oncology research collaborations.
First up, Daiichi Sankyo and Puma Biotechnology (Nasdaq: PBYI) announced a preclinical research collaboration with Memorial Sloan Kettering Cancer Center (MSK) to explore the combination of Daiichi Sankyo’s investigational antibody drug conjugate DS-8201 and Puma Biotechnology’s irreversible pan-HER tyrosine kinase inhibitor Nerlynx (neratinib) in HER2-mutated or HER2-positive solid tumors.
Specifically, investigators will use disease models to assess the susceptibility of HER+ tumors to DS-8201, neratinib and other HER2-targeting therapies, further clarify mechanisms of action, the synergy of combination approaches and tumor resistance to therapy.
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