Daiichi Sankyo halts nimotuzumab Ph III trial in lung cancer
Japanese drug major Daiichi Sankyo (TYO: 4568) says that it has discontinued the Phase III clinical trial conducted in Japan for nimotuzumab (DE-766) in lung cancer due to safety concerns.
The Phase III clinical trial was a multicenter, randomized, double-blind, placebo-controlled study investigating nimotuzumab for first-line therapy in patients with unresectable and locally advanced squamous cell lung cancer. Patients received either nimotuzumab in combination with concurrent chemo-radiotherapy or a placebo in combination with concurrent chemo-radiotherapy.
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