According to recent syndicated reports on the management of renal anemia in the USA, familiarity with biotechnology giant Amgen's clinical trial TREAT has increased and around 90% of nephrologists are at least somewhat familiar with the study.
Close to two-thirds report the study had led to changes or expected changes in their use of erythropoietin stimulating agents (ESAs) in chronic kidney disease non-dialysis (CKD-ND) patients; the study has also led to changes in anemia management in dialysis patients, albeit to a lesser extent. Impact appears to be on the ESA class as a whole, effecting both Amgen's Aranesp (darbepoetin alfa) and Epogen (epoetin alfa) and Centocor Ortho Biotech's Procrit (epoetin alfa), say the reports from BioTrends.
Lower safety ratings for ESAs
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