Carrick and Menarini to evaluate samuraciclib and elacestrant combo

20 December 2022

Ireland-based cancer focused biopharma Carrick Therapeutics and family-owned Italian pharma Menarini have announced a clinical trial collaboration and supply agreement.

This agreement covers the execution of a Phase II clinical trial to evaluate the novel combination of Carrick’s samuraciclib (CT7001), an oral and first-in-class inhibitor of CDK7, and Menarini‘s oral selective estrogen receptor degrader (SERD), elacestrant, in patients with CDK4/6i resistant HR+, HER2- metastatic breast cancer.

Menarini and Carrick will jointly sponsor the clinical trial. Elacestrant is currently under regulatory review in the USA and Europe.

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