Transdermal cannabinoid specialist Zynerba Pharmaceuticals (Nasdaq: ZYNE) suffered a sharp shock to its share price in pre-market trading, as the firm revealed its Phase I trial of ZYN001 had flopped.
The top-line data show that trial participants given the pro-drug of tetrahydrocannabinol (THC) had not achieved target blood levels of 5 to 15ng/ml THC.
The firm said it would focus its development efforts and investments on ZYN002, a change that it says will extend its cash runway into the second half of 2019.
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