Health Canada has granted marketing authorization for Quviviq (daridorexant) for the management of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance.
Idorsia’s (SIX: IDIA) dual orexin receptor antagonist (DORA) acts on both orexin 1 and orexin 2 receptors equipotently. Rather than inducing sleep through broad inhibition of brain activity, Quviviq blocks only the activation of orexin receptors which promote wakefulness.
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