Cabometyx and Tecentriq come good in late-stage prostate cancer

22 August 2023

Exelixis (Nasdaq: EXEL) and Ipsen (Euronext: IPN) have announced that the Phase III CONTACT-02 pivotal trial met one of two primary endpoints, demonstrating a statistically-significant improvement in progression-free survival (PFS) at the primary analysis.

CONTACT-02 is studying a combination of their partnered-drug cabozantinib, which is marketed as Cabometyx, alongside atezolizumab, a Roche (ROG: SIX) immunotherapy branded as Tecentriq.

"We look forward to discussing these findings with the US Food and Drug Administration"The trial is comparing the combination with a second novel hormonal therapy in patients with metastatic castration-resistant prostate cancer (mCRPC) and measurable soft tissue disease who have been previously treated with one novel hormonal therapy.

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