UK-based AstraZeneca (LSE: AZN) has picked up a new indication in the USA for Brilinta (ticagrelor), to reduce the risk of a first heart attack or stroke in high-risk patients with coronary artery disease (CAD).
The approval was based on positive results from the Phase III THEMIS trial, which met its primary endpoint, showing a statistically-significant reduction in heart attack and stroke.
While the therapy was once forecast to have the potential for multi-billion dollars in sales, it took six years for the drug to reach blockbuster status, a fact attributed to a relatively high price compared with alternatives in the market.
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