Under their TAK-935/OV935 program, Japan’s Takeda and USA-based Ovid Therapeutics plan to initiate three clinical trials:
These trials join the clinical development program that includes a fully enrolled Phase Ib/IIa trial of adults with DEE.
Together, these trials will further investigate the potential of TAK-935/OV935 to modulate the N-Methyl-D-Aspartate (NMDA) signaling receptor, which has been implicated in several neurologic disorders.
“Takeda and Ovid believe that TAK-935/OV935, with its novel mechanism of action, may have the potential to treat rare epilepsies.” said Emiliangelo Ratti, head of the Neuroscience Therapeutic Area Unit at Takeda.
“The expansion of our clinical program to include pediatric populations, and additional rare epilepsies, exemplifies our joint commitment to identify an innovative treatment option for DEE,” he added.
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