Bold data support possible COVID-19 antiviral

17 August 2020

Canadian clinical-stage biotech Bold Therapeutics has revealed data which it says supports “rapid clinical development” of BOLD-100 as a novel antiviral against COVID-19.

In April, the Vancouver-based firm partnered with the University of Ottawa to explore the potential utility of the candidate as a novel antiviral agent, adding to a range of collaborations with academic centers around the world.

Under development as an anti-cancer drug, BOLD-100 works by blocking stress-induced upregulation of GRP78, which is thought to play a critical role in host recognition, viral entry and viral replication.

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