Blueprint releases promising data for Ayvakit in indolent SM

27 February 2023
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Coming back from a major partnership disappointment last week, Boston, USA-based biotech Blueprint Medicines (Nasdaq: BPMC) has now released positive results from the PIONEER trial of Ayvakit (avapritinib) in patients with indolent systemic mastocytosis (SM).

The data were presented at the American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting.

In addition to previously reported top-line results demonstrating statistically-significant and clinically-meaningful improvements on the primary and all key secondary endpoints, new detailed results further highlight the benefits of Ayvakit on pathological mast cell burden, disease symptoms and quality of life:

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