Biogen ends Sage collab after negative trial results

27 September 2024

Sage Therapeutics (Nasdaq: SAGE) has announced that Biogen (Nasdaq: BIIB) has terminated its partnership on the SAGE-324 program, following the recent failure of the drug in a Phase II study for the treatment of essential tremor.

The decision comes after the companies revealed negative results from the KINETIC 2 trial.

Sage will regain full ownership of the drug, a neuroactive steroid that modulates GABAA receptors, and will explore other potential applications in different neurological conditions.

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