AstraZeneca reports positive results from Phase III antibiotic study

19 August 2014

Anglo-Swedish drug major AstraZeneca (LSE: AZN) has achieved positive results from the pivotal Phase III studies investigating the potential of the antibiotic ceftazidime-avibactam (CAZ-AVI) in the treatment of complicated intra-abdominal infections in hospitalized adults.

The drug consists of a cephalosporin (ceftazidime), which is an established treatment for serious bacterial infections, and a non-beta lactam beta-lactamase inhibitor (avibactam). It is being developed to treat various gram-negative bacterial infections which are becoming increasingly threatening to public health as antibiotic resistance increases.

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