AstraZeneca in-licenses novel agent for cardiometabolics and obesity

9 November 2023

China-headquartered Eccogene has entered into an exclusive license agreement with AstraZeneca (LSE: AZN) under which the UK pharma major will develop and commercialize Eccogene's small molecule GLP-1 receptor agonist (GLP-1RA) ECC5004 for the potential treatment of obesity, type-2 diabetes and other comorbidities.

Preliminary results from the Phase I trial have shown a differentiating clinical profile for ECC5004, with good tolerability and encouraging glucose and body weight reduction across the dose levels tested compared to placebo.

AstraZeneca is granted exclusive global rights for the development and commercialization of ECC5004 for any indication in all territories except China, where Eccogene has the right to co-develop and co-commercialize in China alongside AstraZeneca.

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