Despite an appeal by AstraZeneca (LSE: AZN), the National Institute of Health and Care Excellence (NICE) has published final guidance that does not recommend the use of its drug Tagrisso (osimertinib) in a lung cancer indication.
The cost-effectiveness watchdog rejected AstraZeneca’s attempts to have the treatment provided within National Health Service in England, in line with its licensed indication, for untreated locally-advanced or metastatic epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) in adults.
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