ASCO 2019: Lynparza beats chemotherapy in relapsed BRCA-mutated advanced ovarian cancer

4 June 2019

Anglo-Swedish pharma major AstraZeneca (LSE: AZN) and US drug giant Merck & Co (NYSE: MRK) have presented further evidence in support of Lynparza (olaparib) at the 2019 ASCO meeting.

Based on results in the Phase III SOLO3 trial, Lynparza is the first PARP inhibitor to demonstrate efficacy over chemotherapy in relapsed BRCA-mutated advanced ovarian cancer following response to platinum-based chemotherapy.

"We look forward to working closely with regulatory authorities to include findings from this trial in the prescribing information"There was a statistically-significant and clinically-meaningful improvement in objective response rate, as there was in progression-free survival, with Lynparza patients living without the disease advancing for an average of four months longer.

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