Arrowhead to advance obesity drug candidates into clinic

16 August 2024

Californian company Arrowhead Pharmaceuticals (Nasdaq: ARWR) has revealed plans to advance two RNA interference (RNAi) drug candidates into clinical studies.

The Pasadena-based firm is targeting obesity and metabolic diseases with the candidates, ARO-INHBE and ARO-ALK7, which have shown promise in preclinical trials.

The firm said the novel drugs had demonstrated potential to reduce body weight and fat mass while preserving lean muscle mass.

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