Ardelyx signs tenapanor license deal in Canada

19 March 2018
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US drugmaker Ardelyx (Nasdaq: ARDX) has entered into license agreement with Canadian firm Knight Therapeutics (TSX: GUD) providing the latter with exclusive rights to commercialize tenapanor in Canada.

Tenapanor is Ardelyx' oral, first-in-class small molecule treatment that has completed Phase III development for irritable bowel syndrome with constipation (IBS-C) and is being evaluated in a second Phase III study for hyperphosphatemia.

Under the terms of the accord, Ardelyx is eligible to receive up to C$25 million ($19.2 million) in total payments including an upfront payment and development and sales milestones, as well as double-digit tiered royalties on net sales. Knight will have the exclusive rights to market and sell tenapanor in Canada.

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