Aptinyx loses a third of its value on fibromyalgia failure

15 August 2022

Chicago-based Aptinyx (Nasdaq: APTX), a clinical-stage biopharmaceutical company developing therapies for the treatment of brain and nervous system disorders, has announced disappointing results from a Phase IIb study evaluating the effects of NYX-2925 in patients with fibromyalgia.

NYX-2925 did not achieve statistically-significant separation from placebo on the study’s primary endpoint, which assessed the change from baseline in average daily pain on the numeric rating scale. Following the news, the company's share price closed 32% down on Friday.

"The results of this study highlight the challenges of developing novel therapies for pain"

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