Another AstraZeneca GLP-1 agonist bites the dust

21 June 2023

Anglo-Swedish pharma major AstraZeneca (LSE: AZN) is to drop the GLP-1 agonist, AZD0186, which had been in a Phase I trial in type 2 diabetes.

The Cambridge-based firm had previously hoped to compete with other drugmakers in the GLP-1 space, particularly Novo Nordisk’s (NOV: N) market leader semaglutide, which is sold under the brand names Ozempic, Wegovy and Rybelsus, and is kicking up a storm in the obesity market.

But AstraZeneca’s hopes were dashed by disappointing data that has led the company to abandon its development of the candidate.

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