Shares in Altimmune (Nasdaq: ALT) lost more than half of their value on Tuesday.
The US biopharma earlier announced top-line results from a week 24 interim analysis of 160 subjects in its 48-week MOMENTUM Phase II obesity trial of pemvidutide.
Of most concern to investors was likely the figure that, at the strongest 2.4mg dosage of pemvidutide, as many as 11, or 27%, of patients discontinued treatment due to adverse events (AEs). This was 10 times higher than the rate with placebo and around three times higher than the rate with the weaker two doses, of 1.2mg and 1.8mg.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze