Altimmune's obesity hopes slimmed down by setback

22 March 2023
obesity_big

Shares in Altimmune (Nasdaq: ALT) lost more than half of their value on Tuesday.

The US biopharma earlier announced top-line results from a week 24 interim analysis of 160 subjects in its 48-week MOMENTUM Phase II obesity trial of pemvidutide.

Of most concern to investors was likely the figure that, at the strongest 2.4mg dosage of pemvidutide, as many as 11, or 27%, of patients discontinued treatment due to adverse events (AEs). This was 10 times higher than the rate with placebo and around three times higher than the rate with the weaker two doses, of 1.2mg and 1.8mg.

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK

Companies featured in this story

More ones to watch >


Today's issue

Company Spotlight





More Features in Pharmaceutical