Additional data confirm promise of acoramidis as ATTR-CM treatment
US genetic diseases and cancer drug developer BridgeBio Pharma (Nasdaq: BBIO) has announced positive results of five new analyses of clinical endpoint events from its Phase III ATTRibute-CM study of acoramidis in transthyretin amyloidosis cardiomyopathy (ATTR-CM).
These new analyses were shared in oral presentations and posters at the 2024 International Symposium of Amyloidosis (ISA). ATTRibute-CM was designed to study the efficacy and safety of acoramidis, an investigational, next-generation, orally administered, highly potent, small molecule stabilizer of TTR.
The only drug currently available for the treatment of TTR cardiomyopathy is Pfizer’s Vyndamax (tafamidis), which generated $3.3 billion in sales last year.
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