Aclaris backers see investments decimated by program failure

14 November 2023

Aclaris Therapeutics (Nasdaq: ACRS) stock has taken a battering again, after the Phase IIb ATI-450-RA-202 trial was found to have missed its primary and secondary endpoints.

The American biotech, which is focused on developing novel drugs for immuno-inflammatory diseases, is trialing the oral MK2 inhibitor zunsemetinib.

The company faced a similar setback in March, when the candidate failed to show a treatment benefit in another mid-stage study, enrolling people with the chronic skin condition hidradenitis suppurativa.

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