AbbVie acquires Syndesi to strengthen neuroscience portfolio

1 March 2022

Syndesi Therapeutics has been acquired by AbbVie (NYSE: ABBV) for up to $1 billion, which will help to expand AbbVie’s neuroscience portfolio.

This acquisition gives AbbVie access to Syndesi’s portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. The mechanism is currently being evaluated for the potential treatment of cognitive impairment and other symptoms associated with a range of neuropsychiatric and neurodegenerative disorders, such as Alzheimer’s disease and major depressive disorder.

Belgium-based Syndesi was established in 2018 by an investor syndicate led by Novo Seeds and Fountain Healthcare together with Johnson & Johnson Innovation - JJDC, V-BIO Ventures, the Walloon Investment Fund (SRIW) and VIVES Louvain Technology Fund, leveraging Belgian drugmaker UCB's (Euronext: UCB) neurology expertise in modulating the synaptic vesicle protein SV2A.

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