Progress in Alzheimer's treatment has been frustratingly slow and researchers have struggled to comprehend the mechanisms of a condition that varies greatly in severity and speed of progression.
Pharma has been rocked by costly late-stage failures, with many drugs showing promise in the lab, only to flop in large-scale clinical trials, and no new novel Alzheimer's therapeutic has been approved since Namenda (memantine) in 2003.
The rising prevalence of Alzheimer's - the most common dementia-causing disease - puts a huge strain on health and care systems, making effective treatments a priority. The World Alzheimer's Report of 2015 reveals that if global dementia care were a country, it would now be the world's 18th largest economy, on course to become a trillion dollar cost by 2018.
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