AAIC 2023: New Alzheimer's data from TauRx sees reduction in neurodegeneration

17 July 2023

On Sunday, Singapore-headquartered TauRx Pharmaceuticals presented new data from the Phase III LUCIDITY trial that measured the impact of the company’s drug candidate, hydromethylthionine mesylate (HMTM), on neurofilament light chain (NfL), an established biomarker for brain neurodegeneration.

The results were presented during an oral presentation at the Alzheimer’s Association International Conference (AAIC) in Amsterdam, Netherlands.

TauRx noted that the blood concentration of NfL showed a statistically-significant 93% reduction in change over 12 months in participants receiving HMTM at a dose of 16mg/day relative to the control group, which correlated significantly with a tau biomarker (p-tau 181) in blood.

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