Biomea Fusion
A clinical stage biopharmaceutical company developing covalent small molecules to treat genetically defined cancers and metabolic diseases.
The company's proprietary FUSION System is being used to discover, design and develop a pipeline of next-generation covalent-binding small molecule medicines.
Biomea's lead product candidate, BMF-219, is designed to be an orally bioavailable, potent, and selective covalent inhibitor of MENIN, a transcriptional regulator known to play a direct role in oncogenic signaling in multiple cancers. In June 2024, Biomea erceived notice from the US FDA that a full clinical hold has been placed on the company's Phase I/II clinical trials of BMF-219 in type II and type I diabetes.
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