The Pharmaletter

One To Watch

Alligator Bioscience

A clinical-stage biotechnology company developing tumor-directed immuno-oncology antibody drugs.

Alligator’s portfolio includes several promising drug candidates, with the CD40 agonist mitazalimab as its key asset. Furthermore, Alligator is co-developing ALG.APV-527 with Aptevo Therapeutics, several undisclosed molecules based on its proprietary technology platform, Neo-X-Prime, and novel drug candidates based on the RUBY bispecific platform with Orion Corporation. Out-licensed programs include AC101/HLX22, in Phase II development as of Q1 2024, by Shanghai Henlius Biotech and an undisclosed target to Biotheus.

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