Novocure close to regulatory filing on results from Phase III PANOVA-3 trial

2 December 2024

Switzerland-based Novocure (Nasdaq: NVCR) saw its shares leap 38% to $27.64 as it revealed positive results from the pivotal, Phase III PANOVA-3 trial, demonstrating a statistically-significant improvement in median overall survival (mOS) versus control.

The PANOVA-3 study evaluated the use of Tumor Treating Fields (TTFields) therapy concomitantly with gemcitabine and nab-paclitaxel as a first-line treatment for unresectable, locally advanced pancreatic adenocarcinoma.

As a result, Novocure says it plans to file for regulatory authorization in the USA, European Union, Japan and other key market. Its China marketing partner, Zai Lab (HKEX: 9688), also said it plans to file for regulatory approval in China.

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