New recommendations for GLP-1 receptor agonists from PRAC

13 July 2024

Following its July 2024 meeting, the European Medicines Agency’s (EMA) safety committee (PRAC) has recommended new measures on the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs).

The aim is to minimize the risk of aspiration and pneumonia aspiration reported in patients taking GLP-1 RAs who undergo surgery with general anesthesia or deep sedation. GLP-1 RAs are medicines used for treatment of type 2 diabetes and obesity.

Notable among such products are Novo Nordisk’s (NOV: N) semaglutide, marketed under the trade name Wegovy for obesity and Ozempic for diabetes, and Eli Lily’s tirzepatide, sold as Mounjaro and Zepbound.

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