Merck cuts pair of Keytruda trials

30 August 2024

While it may already be one of the world’s top-selling drugs across any therapy area, Merck & Co’s (NYSE: MRK) Keytruda (pembrolizumab) has not been successful in every indication and combination that it has been tried in across the anti-PD-1 therapy’s vast development program in oncology.

Merck added a couple more to the unsuccessful column on Thursday in announcing updates on two Phase III trials, KEYNOTE-867 and KEYNOTE-630.

The US pharma giant is discontinuing KEYNOTE-867 evaluating Keytruda in combination with stereotactic body radiotherapy (SBRT) for the treatment of patients with stage I or II non-small cell lung cancer (NSCLC), including those who are medically inoperable or have refused surgery.

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