Radioligand therapies (RLTs) have received prominent attention from major pharmaceutical companies in treating prostate cancer.
Germany-based Bayer (BAYN: DE) Xofigo (radium-223 dichloride) demonstrated the proof-of-concept with its Food and Drug Administration (FDA approval for castration-resistant prostate cancer (CRPC). Interest in RLTs has since peaked, with Swiss giant Novartis (NOVN: VX) acquiring developer Advanced Accelerator Applications and the highly effective Pluvicto (lutetium [177Lu] vipivotide tetraxetan), targeting prostate-specific membrane antigen (PSMA).
Against this backdrop, radiopharmaceuticals for prostate cancer are expected to go nuclear, recording $6.3 billion in sales by 2030, according to pharma analytics company GlobalData.
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