Spanish drugmaker PharmaMar has licensed analogs of Kahalalide F for uses outside of oncology and neurology to German firm Marinomed Biotechnologie GmbH.
The novel depsipeptide is derived from the Hawaiian sea slug Elysia rufesceus. In preclinical assays performed by Marinomed, certain synthetic analogs of Kahalalide F have shown a favorable activity profile.
As part of the agreement, PharmaMar will collaborate with Marinomed in identifying and synthesizing the most suitable drug candidates and will retain all rights to Kahalalide F analogs for the treatment of cancer and central nervous systems disorders together with all rights on Kahalalide F itself and two of its related analogs.
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