MacroGenics gets $100 million milestone from Incyte
US drug developer MacroGenics (Nasdaq: MGNX) yesterday announced the achievement of $100 million in milestones from Incyte Corp (Nasdaq: INCY) related to development progress of Zynyz (retifanlimab-dlwr), following an agreement on July 24, 2024, pursuant to es were deemed to have been met.
Zynyz is an intravenous PD-1 inhibitor indicated in the US for the treatment of adult patients with metastatic or recurrent locally advanced Merkel cell carcinoma. The drug was approved by the US Food and Drug Administration (FDA) in March last year.
Zynyz is a monoclonal antibody initially developed by MacroGenics and licensed to Incyte under a 2017 exclusive global collaboration and license agreement. Incyte and its collaborators continue to pursue development of retifanlimab in other indications, which include both monotherapy and combination regimens.
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