Leqvio and Repatha to spearhead lipid-modifying agents market resurgence

5 July 2024

The lipid-modifying agents market, which had seen a dramatic decline over the past decade, is now set for a spectacular revival, driven by the innovating therapies Leqvio (inclisiran) from Swiss pharma giant Novartis (NOVN: VX) and Repatha (evolocumab) from US biotech Amgen (Nasdaq: AMGN).

These two treatments are forecast to spreadhead the market’s resurgence, bringing it back to prominence by 2030, according to pharma analytics company GlobalData.

The lipid-modifying agents market has been facing a significant downturn since 2011 due to the expiration of patents of blockbuster drugs. Among the most notable losses was Lipitor (atorvastatin) from Viatris (Nasdaq: VTRS), which accounted for a staggering $11 billion in sales in 2011, nearly 39% of the market. Following its loss of exclusivity, Lipitor’s sales plummeted by 56% within just a year due to intense competition from generic versions.

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