Karyopharm Therapeutics sells ALS candidate to Biogen for up to $217 million

25 January 2018

Karyopharm Therapeutics (Nasdaq: KPTI) is to sell its investigational oral SINE compound KPT-350 to fellow Massachusetts-based biotech firm Biogen (Nasdaq: BIIB) in a deal worth up to $217 million.

SINE compounds are a family of small-molecule drugs that inhibit certain processes, resulting in reduced inflammation and neurotoxicity, and increased neuroprotective responses.

Lead candidate KPT-350 is a potential therapy for amyotrophic lateral sclerosis (ALS).

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