J&J’s SC Tremfya could set new standard in Crohn's disease treatment

22 October 2024

US healthcare giant Johnson & Johnson’s (NYSE: JNJ) subcutaneous (SC) Tremfya (guselkumab) demonstrated strong results in the Phase III GRAVITI trial, marking a major breakthrough in the treatment of Crohn's disease (CD).

This patient-friendly regimen could enhance patient autonomy, improve adherence, and lead to better outcomes. The GRAVITI results position guselkumab as a significant new option in CD, says pharma analytics company GlobalData.

Guselkumab showed efficacy at both induction and maintenance using the new formulation, which is a significant advancement over current therapies that utilize an intravenous (IV) formulation for induction and SC for maintenance. The trial results will be presented in detail at the upcoming American College of Gastroenterology (ACG) 2024 conference on October 25-30.

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