J&J drops antiviral for the prevention of dengue

7 October 2024

US healthcare giant Johnson & Johnson (NYSE: JNJ) revealed it is discontinuing the Phase II field study (NCT05201794) evaluating the efficacy of investigational antiviral candidate mosnodenvir for the prevention of dengue virus in adults aged 18-65 years.

J&J explained the decision as being part of a strategic reprioritization of the company’s communicable diseases research and development (R&D) portfolio. No safety issues were identified.

Efficacy data from the Phase II field study will be available once the final data analyses, which are now underway, are complete. Study investigators have been notified of the discontinuation. All participants have completed the study per protocol and will be notified of the results once they are ready.

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