Ipsen’s CaboNivo shows sustained benefits in aRCC

11 February 2025

French drugmaker Ipsen (Euronext: IPN) today released final results from the Phase III CheckMate -9ER trial of Cabometyx (cabozantinib) in combination with nivolumab (CaboNivo) versus sunitinib in people living with previously untreated advanced renal cell carcinoma (aRCC).

Ipsen noted that these final data demonstrated sustained superior efficacy benefits for the combination versus sunitinib over more than five years, extending survival and prolonging time to tumor progression regardless of risk classification based on International Metastatic Renal Cell Carcinoma Database Consortium scores.

An oral presentation of these data by Dr Robert Motzer will take place at the American Society of Clinical Oncology Genitourinary Symposium on February 13-15, 2025 in San Francisco, CA. (Abstract #439).

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