Investors unsure on Corbus data for potential Padcev rival

17 February 2025

US drugmaker Corbus Pharmaceuticals Holdings (Nasdaq: CRBP) closed Friday’s trading 10% lower.

Corbus earlier announced the presentation of data from its US and UK conducted first-in-human dose escalation clinical study of CRB-701 (SYS6002) at the 2025 American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU).

CRB-701 is a nectin-4-directed antibody-drug conjugate (ADC) that Corbus is developing with China’s CSPC Pharmaceutical Group (HKG: 1093). 

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