Pharmaceutical Carole Longson spent eight years developing novel pharmaceuticals at GlaxoSmithKline, before crossing the floor to join the UK’s national health watchdog, the National Centre for Health and Care Excellence (NICE). The Pharma Letter speaks with her about the importance of cost-effectiveness, the value of the revised Cancer Drugs Fund, the growing role played by real-world evidence, and her hopes for a positive decision on Kadcyla (trastuzumab emtansine). 8 February 2017