- A Phase I trial of a second-generation primatized anti-CD4 antibodyin development for the treatment of rheumatoid arthritis, IDEC-151/SB217969, has demonstrated several positive results, according to IDEC Pharmaceuticals. No depletion in CD4 cells or infusion-related adverse events have been noted. Furthermore, when given at high doses, it provided longer receptor binding compared with the first generation antibody, IDEC-CE9/SB210396.
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