GSK’s depemokimab scores well in CRSwNP trials

14 October 2024

UK pharma major GSK (LSE: GSK) today announced positive headline results from two Phase III clinical trials, ANCHOR-1 and ANCHOR-2, which assessed the efficacy and safety of depemokimab versus placebo in adults with chronic rhinosinusitis with nasal polyps (CRSwNP).

Both trials met their co-primary endpoints of a change from baseline in total endoscopic nasal polyp score at 52 weeks and change from baseline in mean nasal obstruction score from weeks 49 to 52.

The overall incidence and severity of treatment-emergent adverse events across both trials were similar in patients treated with either depemokimab or placebo. Further analysis of these data is ongoing. The full results of ANCHOR-1 and ANCHOR-2 will be presented at an upcoming scientific congress.

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