Gritstone goes under after gruesome year

10 October 2024

US vaccine company Gritstone bio (Nasdaq: GRTS) has filed for bankruptcy.

This follows the presentation of disappointing data earlier this year from the Phase II portion of the Phase II/III study evaluating GRANITE, Gritstone’s personalized neoantigen cancer vaccine, in front-line metastatic microsatellite stable colorectal cancer (MSS-CRC). 

Even before those underwhelming results, the company had announced an approximately 40% reduction of its workforce, this coming after a delay to the proposed CORAL Phase IIb study of prophylactic samRNA vaccines in COVID-19.

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