Gritstone further eroded by cancer vaccine latest

2 October 2024

US vaccine company Gritstone bio closed 62% lower after Tuesday’s trading after releasing disappointing news.

The Californian company earlier provided interim Phase II data an ongoing study evaluating GRANITE, its individualized neoantigen targeting immunotherapy, in frontline microsatellite stable colorectal cancer (MSS-CRC).

This randomized, controlled study is designed to evaluate the clinical benefit of maintenance therapy with GRANITE in combination with immune checkpoint inhibitors in addition to fluoropyrimidine/bevacizumab, versus fluoropyrimidine/bevacizumab alone.

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