GLP-1R gold rush: emerging biotechs set to challenge market leaders

14 January 2025

The glucagon-like peptide-1 receptor (GLP-1R) market experienced significant growth in 2023, generating $37.2 billion in sales, with Denmark’s Novo Nordisk (NOV: N) and US major Eli Lilly (NYSE: LLY) dominating the sector.

However, emerging biotech companies are poised to disrupt this landscape, with promising pipeline products expected to generate substantial revenue and challenge the market leaders by 2030, says pharma analytics company GlobalData.

Currently, there are 323 active GLP-1Rs in the pipeline, with several estimated to deliver significant returns upon launch. While mega-cap companies dominate the GLP-1R market and are expected to maintain their stronghold in 2030, three smaller biotechs - Viking Therapeutics (Nasdaq: VKTX), Altimmune (Nasdaq: ALT), and Structure Therapeutics (Nasdaq: GPCR) - are emerging as potential disruptors in this drug category, giving hope to innovative newcomers.

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