Genmab’s Tivdak approved in Japan

27 March 2025

Danish cancer specialist Genmab (OMX: GEN) today announced that the Japanese Ministry of Health, Labor and Welfare has approved Tivdak (tisotumab vedotin) for the treatment of advanced or recurrent cervical cancer that has progressed on or after cancer chemotherapy.

Tivdak is the first and only ADC to be approved for people living with cervical cancer in Japan, noted Genmab, whose shares rose 3.2% to 1,399 kroner on the news.

The drug was developed by Seagen, now a part of US pharma giant Pfizer (NYSE: PFE), and Genmab. Tivdak is now co-owned by Genmab and Pfizer, under an agreement in which the companies share costs and profits for the product on a 50:50 basis.

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